I stumbled upon this little ditty today:
Garfield Minus Garfield
Who would have guessed that when you remove Garfield from the Garfield comic strips, the result is an even better comic about schizophrenia, bipolor disorder, and the empty desperation of modern life? Friends, meet Jon Arbuckle. Let’s laugh and learn with him on a journey deep into the tortured mind of an isolated young everyman as he fights a losing battle against lonliness and methamphetamine addiction in a quiet American suburb.
I have to say, reading some of the more bizarro-hilarious ones such as this or this or this reminds me of one of my brothers. Ahem. Sometimes. When he's hopped up on too much Arby's.